N-Cyclopropyl-N-Methylpemoline (also known as N-Methyl-Cyclazodone or NMC) is a novel stimulant substance of the 4-oxazolidinone class. is structurally related to thozalinone and
cyclazodone. Similar to amphetamine, the addition of the methyl group on cyclazodone is thought to increase its potency and duration. The mechanism of action involves promoting the
release of dopamine, norepinephrine, and serotonin in the brain.
Unlike cyclazodone, N-methyl-cyclazodone has little to no history of use and only recently emerged as a study aid. Its non-clinical use has only found recent attention as a
research chemical study aid or atypical antidepressant. It should be noted that the lack of pharmacological data and extremely limited history of human usage pose considerable
concern regarding its long-term use as a substitute for prescription stimulants or antidepressants. Similar to methamphetamine, this substance is reported to possess an usually
long duration, it is therefore recommended to take one's dose in the morning and avoid redosing.
Subjective effects include stimulation, focus enhancement, stamina enhancement, increased blood pressure, and mild euphoria. Some anecdotal reports suggest that N-methyl-cyclazodone
and its parent compound cyclazodone may have nootropic properties similar to central nervous system stimulants such as methylphenidate and amphetamine.
One of its parent compounds, thozalinone, has been used as an antidepressant in Europe, which may be due to its serotonin-releasing properties.
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N-Methyl-Cyclazodone stock last updated at: December 2024
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